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| Document
Summary |
| Title |
Antioxidants in Pre-eclampsia |
| Description |
Antioxidants, pregnancy, oxidative stress, clinical predictors |
| Creation Date |
01 June 1999 |
| Doc type |
Article |
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| Document
Abstract: |
| Pre-eclampsia is a systemic pregnancy syndrome, characterised by reduced uteroplacental blood flow, diffuse endothelial dysfunction, increased peripheral vascular resistance, hypertension, coagulation abnormalities, elevations of maternal leukocyte-derived cytokines, hyperlipidemia, proteinuria, and oedema. The hypotheses suggest reactive oxygen species or their metabolites (oxidative stress) ultimately compromise the "defensive" vasodilatory, anti-aggregatory, and barrier functioning of the vascular endothelium due to uncontrolled lipid oxidation. |
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